Publications

• Larison, B., Pinho, G. M., Hagani, A., Zoller, J. A., Li, C. Z., Finno, C. J., Farrell, C., Kaelin, C. B., Barsh, G. S., Wooding, B., Robeck, T. R., Maddox, D., Pellegrini, M. & Horvath, S. Epigenetic models predict age and aging in plains zebras and other equids. bioRxiv (2021)
• Pinho, G. M., Martin, J. G. A., Farrell, C., Haghani, A., Zoller, J. A., Zhang, J., Snir, S., Pellegrini, M., Wayne, R. K., Blumstein, D. T. & Horvath, S. Hibernation slows epigenetic aging in yellow-bellied marmots. BioRxiv 2021.03.07.434299 (2021)
• Farrell, C., Thompson, M., Tosevska, A., Oyetunde, A. & Pellegrini, M. BiSulfite Bolt: A BiSulfite Sequencing Analysis Platform. GigaScience (2021)
• Li, S., Ma, F., Yokota, T., Jr., G. G., Palermo, A., Wang, Y., Farrell, C., Wang, Y.-C., Wu, R., Zhou, Z., Pan, C., Morselli, M., Teitell, M. A., Ryazantsev, S., Fishbein, G. A., ten Hoeve, J., Arboleda, V. A., Bloom, J., Dillon, B., Pellegrini, M., Lusis, A. J., Graeber, T. G., Arumugaswami, V. & Deb, A. Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2–induced systemic toxicity. JCI Insight 6, (2021).
• Farrell, C., Snir, S. & Pellegrini, M. The Epigenetic Pacemaker: modeling epigenetic states under an evolutionary framework. Bioinformatics 36, 4662–4663 (2020).
• Nowicki, T. S., Farrell, C., Morselli, M., Rubbi, L., Campbell, K. M., Macabali, M. H., Berent-Maoz, B., Comin-Anduix, B., Pellegrini, M. & Ribas, A. Epigenetic Suppression of Transgenic T-cell Receptor Expression via Gamma-Retroviral Vector Methylation in Adoptive Cell Transfer Therapy. Cancer Discov. (2020). doi:10.1158/2159-8290.CD-20-0300
• Morselli, M., Farrell, C., Rubbi, L., Fehling, H. L., Henkhaus, R. & Pellegrini, M. Targeted bisulfite sequencing for biomarker discovery. Methods (2020). doi:10.1016/j.ymeth.2020.07.006
• Wu, R., Ma, F., Tosevska, A., Farrell, C., Pellegrini, M. & Deb, A. Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age. JCI Insight 5, (2020).
• Levine, M., McDevitt, R. A., Meer, M., Perdue, K., Di Francesco, A., Meade, T., Farrell, C., Thrush, K., Wang, M., Dunn, C., Pellegrini, M., de Cabo, R. & Ferrucci, L. A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin. Elife 9, (2020).
• Crowther, M. D., Dolton, G., Legut, M., Caillaud, M. E., Lloyd, A., Attaf, M., Galloway, S. A. E., Rius, C., Farrell, C. P., Szomolay, B., Ager, A., Parker, A. L., Fuller, A., Donia, M., McCluskey, J., Rossjohn, J., Svane, I. M., Phillips, J. D. & Sewell, A. K. Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nat. Immunol. 21, 178–185 (2020).
• Snir, S., Farrell, C. & Pellegrini, M. Human epigenetic ageing is logarithmic with time across the entire lifespan. Epigenetics 14, 912–926 (2019).
• Phillips, J., Farrell, C., Wang, Y., Singal, A. K., Anderson, K., Balwani, M., Bissell, M., Bonkovsky, H., Seay, T., Paw, B., Desnick, R. & Bloomer, J. Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria. Mol. Genet. Metab. 128, 391–395 (2019).
• Orozco, L. D., Farrell, C., Hale, C., Rubbi, L., Rinaldi, A., Civelek, M., Pan, C., Lam, L., Montoya, D., Edillor, C., Seldin, M., Boehnke, M., Mohlke, K. L., Jacobsen, S., Kuusisto, J., Laakso, M., Lusis, A. J. & Pellegrini, M. Epigenome-wide association in adipose tissue from the METSIM cohort. Human Molecular Genetics 27, 1830–1846 (2018).
• Yaish, H. M., Farrell, C. P., Christensen, R. D., MacQueen, B. C., Jackson, L. K., Trochez-Enciso, J., Kaplan, J., Ward, D. M., Salah, W. K. & Phillips, J. D. Two novel mutations in TMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child. Blood Cells Mol. Dis. 65, 38–40 (2017).
• Farrell, C. P., Overbey, J. R., Naik, H., Nance, D., McLaren, G. D., McLaren, C. E., Zhou, L., Desnick, R. J., Parker, C. J. & Phillips, J. D. The D519G Polymorphism of Glyceronephosphate O-Acyltransferase Is a Risk Factor for Familial Porphyria Cutanea Tarda. PLoS One 11, e0163322 (2016).
• Farrell, C. P., Parker, C. J. & Phillips, J. D. Exome sequencing for molecular characterization of non-HFE hereditary hemochromatosis. Blood Cells Mol. Dis. 55, 101–103 (2015).